Upcoming Events
Prof. John Wood
University College of London
'Somatosensation à la mode'
March 20, 2019 4:00 p.m.
MGH - Room A5-131
Amir Minerbi, MD, PhD. Clinical research fellow, AEPMU
Microbiome analysis in fibromyalgic patients
March 27, 2019 4:00 p.m.
MGH Room A5-131
Dr. Wideman's Lab
March 28, 2019 9:30 a.m.
Shriner's Hospital for Children, Room 6.35
Tuan Trang, PhD,
University of Calgary
Killam Lecture, Title TBC
April 16, 2019 4:00 p.m.
Grandpre Communications Centre, MNI
Featured Events
CPS 40th Annual Scientific Meeting
Apr 02 2019
Toronto, Ontario
[link]
David Ginty, PhD, Harvard Medicial School
Oct 10 2019, 4:00 p.m.
Jeanne Timmins Amphitheatre, MNI
2019 Aguayo Lecture
[link]
Featured Paper Archive
  • George NC, Laferriere A, Coderre T. Sex differences in the contributions of spinal atypical PKCs and downstream targets to the maintenance of nociceptive sensitization. Mol Pain. 2019 Mar 11:1744806919840582. doi: 10.1177/1744806919840582 [link]
  • Khoutorsky A, Price TJ. Translational Control Mechanisms in Persistent Pain Trends Neurosci. 2017 Dec 14. pii: S0166-2236(17)30233-3. doi: 10.1016/j.tins.2017.11.006 [link]
  • Häuser W, Sarzi-Puttini P, Fitzcharles MA. Fibromyalgia syndrome: under-, over- and misdiagnosis Clin Exp Rheumatol. 2019 Jan-Feb;37 Suppl 116(1):90-97. Epub 2019 Feb 8 [link]
  • Beaudry H, Daou I, Ase AR, Ribeiro-da-Silva A, Séguéla P. Distinct behavioral responses evoked by selective optogenetic stimulation of the major TRPV1+ and MrgD+ subsets of C-fibers Pain. 2017 Dec;158(12):2329-2339. doi: 10.1097/j.pain.0000000000001016 [link]
  • James G, Klyne DM, Millecamps M, Stone LS, Hodges PW.ISSLS Prize in Basic science 2019: Physical activity attenuates fibrotic alterations to the multifidus muscle associated with intervertebral disc degeneration. Eur Spine J. 2019 Feb 8. doi: 10.1007/s00586-019-05902-9. [link]
  • Martel MO, Petersen K, Cornelius M, Arendt-Nielsen L, Edwards R. Endogenous pain modulation profiles among individuals with chronic pain: Relation to opioid use. J Pain. 2018 Oct 29. pii: S1526-5900(18)30759-4. doi: 10.1016/j.jpain.2018.10.004. [link]
  • Hochberg U, Ojeda A, Brill S, Perez J An internet based survey to assess clinicians' knowledge and attitudes towards opioid induced hypogonadism. Pain Pract. 2018 Sep 30. doi: 10.1111/papr.12731. [link]
  • Anne-Kathrin Brascher, Susanne Becker, Marie-Eve Hoeppli, Petra Schweinhardt Different Brain Circuitries Mediating Controllable and Uncontrollable Pain The Journal of Neuroscience 36(18):5013–5025 (2016) [link]
  • Miller J, Barber D, Donnelly C, French S, Green M, Hill J, MacDermid J, Marsh J, Norman K, Richardson J, Taljaard M, Wideman T, Cooper L, McPhee C. Determining the impact of a new physiotherapist-led primary care model for back pain: protocol for a pilot cluster randomized controlled trial Trials. 2017 Nov 9;18(1):526. doi: 10.1186/s13063-017-2279-7 [link]
  • Mouchbahani-Constance S, Lesperance, LS, Petitjean H,Davidova A, Macpherson A, Prescott SA, Sharif-Naeini R. Lionfish Venom Elicits Pain Predominantly Through the Activation of Non-Peptidergic Nociceptors PAIN: June 29, 2018, doi: 10.1097/j.pain.0000000000001326 [link]
  • Piltonen M, Parisien M, Grégoire S, Chabot-Doré AJ, Jafarnejad SM, Bérubé P, Djambazian H, Sladek R, Geneau G, Willett P, Stone LS, Shabalina SA, Diatchenko L. Alternative Splicing of the Delta-Opioid Receptor Gene Suggests Existence of New Functional Isoforms Mol Neurobiol. 2018 Jul 31. doi: 10.1007/s12035-018-1253-z. [link]
  • Gobbi G, Atkin T, Zytynski T, Wang S, Askari S, Boruff J, Ware M, Marmorstein N, Cipriani A, Dendukuri N, Mayo N. Association of Cannabis Use in Adolescence and Risk of Depression, Anxiety, and Suicidality in Young Adulthood: A Systematic Review and Meta-analysis JAMA Psychiatry. 2019 Feb 13. doi: 10.1001/jamapsychiatry.2018.4500 [link]
  • Tahmasebi S, Khoutorsky A, Mathews MB, Sonenberg N. Translation deregulation in human disease. Nat Rev Mol Cell Biol. 2018 Jul 23. doi: 10.1038/s41580-018-0034-x [link]
  • Cordeiro Matos S, Zamfir M, Longo G, Ribeiro-da-Silva A, Séguéla P. Noradrenergic fiber sprouting and altered transduction in neuropathic prefrontal cortex Brain Struct Funct.doi: 10.1007/s00429-017-1543-7 (Nov 2017) [link]
  • Smith SB et al. Genome-wide association reveals contribution of MRAS to painful temporomandibular disorder in males. Pain. 2018 Nov 13. doi: 10.1097/j.pain.0000000000001438 [link]
  • Ware M.A., Martel M.O., Jovey R., Lynch M.E., Singer J. A prospective observational study of problematic oral cannabinoid use. Psychopharmacology (Berl). 2018 Feb;235(2):409-417. doi: 10.1007/s00213-017-4811-6. Epub 2017 Dec 17. [link]
  • Ehrlich AT, Kieffer BL, Darcq E Current strategies toward safer mu opioid receptor drugs for pain management Expert Opin Ther Targets. 2019 Feb 25. doi: 10.1080/14728222.2019.1586882 [link]
  • Martin LJ, Acland EL, Cho C, Gandhi W, Chen D, Corley E, Kadoura B, Levy T, Mirali S, Tohyama S, Khan S, MacIntyre LC, Carlson EN, Schweinhardt P, Mogil JS. Male-Specific Conditioned Pain Hypersensitivity in Mice and Humans. Curr Biol. 2019 Jan 21;29(2):192-201.e4. doi: 10.1016/j.cub.2018.11.030. Epub 2019 Jan 10 [link]
  • Ihab Daou, Hélène Beaudry, Ariel R. Ase, Jeffrey S. Wieskopf, Alfredo Ribeiro-da-Silva, Jeffrey S. Mogil, Philippe Séguéla Optogenetic Silencing of Nav1.8-Positive Afferents Alleviates Inflammatory and Neuropathic Pain DOI: 10.1523/ENEURO.0140-15 (2016) [link] [File]
  • Massart R, Dymov S, Millecamps M, Suderman M, Gregoire S, Koenigs K, Alvarado S, Tajerian M, Stone LS, Szyf M. Overlapping signatures of chronic pain in the DNA methylation landscape of prefrontal cortex and peripheral T cells. Sci Rep. doi: 10.1038/srep19615 (2016) [link]
  • Tansley, S.N., Macintyre, L. C., Diamond, L., Sotocinal, S.G., George, N., Meluban, L., Austin, J-S., Coderre, T.J., Martin, L.J.,Mogil, J.S.Conditioned pain modulation in rodents can feature hyperalgesia or hypoalgesia depending on test stimulus intensity PAIN: December 03, 2018, doi: 10.1097/j.pain.0000000000001454 [link]
  • Coderre TJ, Topical drug therapeutics for neuropathic pain. Expert Opin Pharmacother. Aug 2018. 19(11):1211-1220. doi: 10.1080/14656566.2018.1501026. [link]
  • Yakobov E., Suso-Ribera C., Vrinceanu T., Adams H., Sullivan MJL. Trait perceived injustice is associated with pain intensity and pain behaviour in participants undergoing an experimental pain induction procedureJ Pain, Nov 2018, https://doi.org/10.1016/j.jpain.2018.11.007 [link]
  • Parisien, Marc, Samoshkin, Alexander, Tansley, Shannon N, Piltonen, Marjo H, Martin, Loren J, El-Hachem, Nehme, Dagostino, Concetta, Allegri, Massimo, Mogil, Jeffrey S, Khoutorsky, Arkady,Diatchenko, Luda. Genetic pathway analysis reveals a major role for extracellular matrix organization in inflammatory and neuropathic pain PAIN: January 03, 2019 - in Press. doi: 10.1097/j.pain.0000000000001471 [link]
  • He BH, Christin M, Mouchbahani-Constance S, Davidova A, Sharif-Naeini R, Mechanosensitive ion channels in articular nociceptors drive mechanical allodynia in osteoarthritis Osteoarthritis and Cartilage, Dec. 2017, 25(12):2091-2099 [link]
  • Wideman TH, Edwards RR, Walton DM, Martel MO, Hudon A, Seminowicz DA. The Multi-modal Assessment Model of Pain: A Novel Framework for Further Integrating the Subjective Pain Experience within Research and Practice. Clin J Pain. 2018 Nov 15. doi: 10.1097/AJP.0000000000000670 [link]
  • James G, Millecamps M, Stone LS, Hodges PW.Dysregulation of the Inflammatory Mediators in the Multifidus Muscle After Spontaneous Intervertebral Disc Degeneration SPARC-null Mice is Ameliorated by Physical Activity. Spine. 2018 Oct 15;43(20):E1184-E1194. doi: 10.1097/BRS.0000000000002656. [link]
  • Tuttle AH, Philip VM, Chesler EJ, Mogil JS.Comparing phenotypic variation between inbred and outbred mice.Nat Methods. 2018 Dec;15(12):994-996. doi: 10.1038/s41592-018-0224-7. [link]
  • Baird R, Ingelmo P, Wei A, Meghani Y, Perez EV, Pelletier H, Auer G, Mujallid R, Emil S, Laberge JM, Puligandla P, Shaw K, Poenaru D. Nebulized analgesia during laparoscopic appendectomy (NALA): A randomized triple-blind placebo controlled trial J Pediatr Surg. 2019 Jan;54(1):33-38. doi: 10.1016/j.jpedsurg.2018.10.029 [link]
  • Khoutorsky A, Uttam S, Wong C, Price TJ. eIF4E-dependent Translational Control: A Central Mechanism for Regulation of Pain Plasticity Front. Genet. | doi: 10.3389/fgene.2018.00470 [link]
  • Gélinas C., Boitor M., Puntillo K.A., Arbour C., Topolovec-Vranic J., Cusimano M.D., Choinière M., Streiner D.L. Behaviors indicative of pain in brain-injured adult patients with different levels of consciousness in the intensive care unit. J Pain Symptom Manage. 2018 Dec 26. pii: S0885-3924(18)31481-7. doi: 10.1016/j.jpainsymman.2018.12.333 [link]
  • Kathleen Vincent, Virginia M. Cornea, Yuh-Jiin I. Jong, André Laferrière, Naresh Kumar, Aiste Mickeviciute, Jollee S. T. Fung, Pouya Bandegi, Alfredo Ribeiro-da-Silva, Karen L. O’Malley & Terence J. Coderre Intracellular mGluR5 plays a critical role in neuropathic pain doi:10.1038/ncomms10604 (2016) [link]